Manually verified microbial gene clusters




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All clusters listed below represent functions that are known to be of microbial origin and were not observed on fully sequenced viral genomes before. For example: the photosystem I psaA gene is represented by a cluster that is listed below (T109), while psbA (T2911), which was found on the genome of cyanophages before, is not listed.
Cluster identification process consisted of two stages:
  • Automatic pipeline, whose details will be available soon in a paper describing the project and its finding, and
  • Manual inspection, in which all microbial gene clusters on viral scaffolds were scanned manually based on strict criteria that were meant to prevent false-positives.
  • All clusters listed below passed the manual inspection. Description of the criteria used for manual inspection is available here.

    Manually verified microbial clusters

    ClusterSizeDescription
    T128 70 Peptidedeformylase
    T1396 58 Glycerol-3-phosphate cytidylyltransferase
    T982 36 Exported protein
    T451 31 Glycinedehydrogenase
    T768 30 Antioxidant, AhpC/Tsa family protein
    T1414 28 Fructose-1,6-bisphosphate aldolase class I
    T100 20 Glycosyltransferase, group 1
    T156 15 Serine hydroxymethyltransferase
    T212 13 NAD(P)H-dehydrogenase subunit D
    T603 13 NAD(P)H-dehydrogenase subunit I
    T17 13 Membrane protein
    T90 13 Phosphoribosylaminoimidazole-succinocarboxamidesynthase
    T1338 12 Glycosyltransferase involved in cell wall biogenesis-like
    T1486 11 NH(3)-dependent NAD+ synthetase NadE
    T71 10 Glycine cleavage system protein P2
    T885 10 Iron-sulfur cluster-binding protein
    T891 8 Phosphorylase
    T327 8 Mannitol-1-phosphate/altronate dehydrogenase
    T198 8 Alkylhydroperoxidereductase/Thiol specific antioxidant/Mal allergen
    T1113 8 Putative NH(3)-dependent NAD synthetase
    T596 8 Scaffold protein
    T158 7 Sugarisomerase (SIS)
    T255 6 Translation initiation factor IF-1
    T1119 6 Coenzyme PQQ biosynthesis protein A
    T445 6 Adenylatekinase
    T444 5 Iron-sulfur cluster insertion protein ErpA
    T883 5 Glycine cleavage system aminomethyltransferase T
    T712 5 Antioxidant, AhpC/TSA family protein
    T446 5 Photosynthesis protein N (psbN)
    T361 5 5'-methylthioadenosine nucleosidase/S-adenosylhomocysteinenucleosidase
    T72 5 Ribosomal protein S21
    T204 4 Photosystem I reaction center subunit IX (PsaJ)
    T1557 4 Photosystem I subunit VII (PsaC)
    T109 4 Photosystem I P700 chlorophyll a apoprotein A1 (PsaA)